|
KMID : 1134819990280030710
|
|
Journal of the Korean Society of Food Science and Nutrition
1999 Volume.28 No. 3 p.710 ~ p.721
|
|
|
A Study on Hyperlipidemia in Koreans - Specially Related to Hematological Characteristics and Risk Factors of Hypercholesterolemia -
|
|
Hwang Geum-Hee
Roh Young-Hee
Heo Young-Ran
|
|
|
Abstract
|
|
|
|
This study was conducted to investigate the hematological characteristics and risk factors of hypercholesterolemia(HC) in Korean. 344 adult men who took the annual health check-ups at D or J hospitals were participated in this cross-sectional study. The subjects were grouped by plasma total cholesterol level into three groups: normal cholesterolemic(n=139), borderline hypercholesterolemic(n=93) and hypercholesterolemic(n=112) groups. The data of systolic and diastolic blood pressure(SBP/DBP), hemoglobin, plasma glucose, albumin and cholesterol levels were collected from medical records. The levels of plasma triglyceride(TG), HDL-C, phospholipid, insulin, apo-A and apo-B were measured. The levels of plasma LDL-C, VLDL-C and atherogenic index(AI) were calculated. The subjects with HC had significantly higher SBP and DBP, albumin, TG, phospholipid, HDL-C, LDL-C, VLDL-C and apo-B level than those of the normal subjects. The relative and attributable risks on HC were 1.59 and 0.18 for hypertension(SBP/DBP≥160/95), 2.08 and 0.35 for hypertriglyceridemia(TG≥400㎎/dl). Plasma total cholesterol level was positively correlated with several hematologic parameters: age(r=0.1242, p＜0.05), DBP(r=0.1194, p＜0.05), albumin(r=0.2029, p＜0.001), plasma TG(r=0.3829, p＜0.001), phospholipid(r=0.6036, p＜0.001), LDL-C(r=0.8572, p＜0.001), HDL-C(r=0.2399, p＜0.001), AI(r=0.3116, p＜0.001), apo-B(r=0.2602, p＜0.05) and Lp(a)(r=0.1372, p＜0.05). However, plasma total cholesterol level was negatively correlated with the levels of Apo-A1(r=-0.2922, p＜0.001), and ABR(r=-0.3598, p＜0.001).
|
|
|
KEYWORD
|
|
|
hypercholesterolemia, hematologic parameters, hypertriglyceridemia
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|